Bioactive Small Molecules
Medchemexpress LLC HY-18613 1mg , CAY10603 CAS:1045792-66-2 Purity:>98%
HY-18613 1mg CAY10603 CAS: 1045792-66-2 CAY10603 (BML-281) is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 (BML-281) also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W000434 100mg Medchemexpress, Fmoc-NH-PEG4-CH2CH2COOH CAS:557756-85-1 Purity:>98%
Medchemexpress, HY-W000434 100mg Fmoc-NH-PEG4-CH2CH2COOH CAS:557756-85-1 Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical ANTIBODY HM43239 10mg
An FLT3 inhibitor (IC50s = 1.1 and 1.8 nM for the WT and ITD mutant, respectively); inhibits VEGFR2 and Syk by 100 and 95%, respectively, at 100 nM; inhibits the growth of MOLM-13 and MV4-11 leukemia cells (GI50s = 5.2 and 1.3 nM, respectively)
Selleck Chemical LLC Neoandrographolide S9157-1MG
Neoandrographolide a principle diterpenoids isolated from A paniculata exerts a wide range of therapeutic actions including immunosuppressant antithrombotic anti-inflammatory antineoplastic anti-viral anti-bacterial anti-diabetic anti-oxidative stress antipyretic anti-edematogenic and anti-nociceptive activities
Cayman Chemical ANTIBODY CX-516 25mg
An AMPA receptor modulator; increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices; accelerates acquisition of a conditioned fear response in rats from 10-50 mg/kg; enhances performance in a spatial DNMS test in rats; reverses dominance between the initially dominant and submissive rat pairs in the rat reduction of submissive behavior model
Medchemexpress LLC Glyoxalase I inhibitor 3 | 1415388-25-8 | 98.1% | 375.42 g/mol | C22H21N3O3 | 5 MG
Glyoxalase I inhibitor 3 is a potent small-molecule inhibitor of glyoxalase I (GLO1) with a reported IC50 of 0.011 μM. It is supplied as a research reagent in milligram quantities for biochemical and pharmacological studies. Key chemical properties include molecular formula C22H21N3O3, molecular weight 375.42 g/mol, and measured purity of approximately 98.06%.
- Potent GLO1 inhibition with IC50 0.011 μM.
- Suitable for in vitro biochemical and cellular research.
- High chemical purity (~98.1%).
- Available in milligram quantities for assay development.
- Chemical formula C22H21N3O3; molecular weight 375.42 g/mol.
Medchemexpress LLC HY-18658 1mg , Siremadlin CAS:1448867-41-1 Purity:>98%
HY-18658 1mg Siremadlin CAS: 1448867-41-1 Siremadlin (NVP-HDM201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC GNE-781
GNE-781 (compound 19) is an orally active highly potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP) with IC50 of 0 94 nM in TR-FRET assay GNE-781 also inhibits BRET and BRD4(1) with IC50 of 6 2 nM and 5100 nM respectively GNE-781 exhibits antitumor activity
Cayman Chemical 4-methoxy Estron 5mg
An active metabolite of estrone; increases the proliferation of HUVECs at 10 and 100 nM
Apexbio Technology LLC Mepiroxol 6968-72-5 10mM (in 1mL DMSO)
Mepiroxol is a small-molecule compound characterized by its ability to form specific interactions with target proteins It engages in salt bridge interactions with arginine residues (such as Arg-153 and Arg-74) and participates in hydrogen bonding via its hydroxyl group with protein residues like Asp-50 and Gly-96 supporting enhanced binding affinity Researchers utilize Mepiroxol for investigations into protein-ligand interaction mechanisms aiding structural biology analyses and guiding drug-design efforts
Apexbio Technology LLC Disulfiram, 5g. Cas: 97-77-8 MFCD: MFCD00009048. Dopamine β-hydroxylase inhibitor
Disulfiram blocks the processing of alcohol in the body by inhibiting acetaldehyde dehydrogenase thus causing an unpleasant reaction when alcohol is consumed. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Flunixin Meglumin, 1g Cas# 42461-84-7
Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity. 42461-84-7. MFCD01725419 IC50: A potent cyclooxygenase inhibitor with IC50 values of 1 nM.Flunixin meglumine serves as a non-narcotic and non-steroidal analgesic agent with antipyretic activities. There are other sizes available. Please inqury us for quote.
Cayman Chemical VEGFR2 Kinase Inhibitor II
A reversible, cell-permeable inhibitor of VEGFR2’s kinase activity (IC50 = 70 nM); less potently inhibits PDGFRβ (IC50 = 920 nM); blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 µM, respectively)